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Genome Guardian

Also known as Genome Guardian, genome guardian, genome-guardian

COMBINE WEAPONS in the microscopic roguelite turret shooter with macroscopic depth. Survive 6 modes using an astounding array of turrets, perks, mutations and power-ups on this psychedelic journey to the heart of the abyss. Shmup Mode turns it into a vertical shoot 'em up!

Last update
22 May 2026
Players now
5

Latest update

Event

Genome Guardian 2 Early Access OUT NOW

WHAT TO EXPECT the current state of Genome Guardian 2 as of its Early Access launch 100h+ of Polished, Playtested Content There's so much to sink your teeth into already. 14 Guardians, 12 Hulls, 11 Platforms, 12 Barrels…

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Update history

Browse past updates and patch notes for this game.

20 updates

Gallery

In-game media

Achievements

Community progression

Top picks from 100 Steam achievements, sorted by player unlock rates.

  • Guardian TurretWelcome to Genome Guardian!98.3%
  • Extract ModeWelcome to Genome Guardian!98.3%
  • Dice TurretAchieve victory in Extract mode.73.2%
  • Extract Mode SAchieve victory in Extract mode at Surface Depth.73.0%
  • Focus TurretResearch for ◇400.54.2%
  • Daisy TurretDiscover all 69 microbes.52.2%